Excess Fluoride Interference with Cystic Fibrosis Transmembrane Conductance Regulator (cftr)
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چکیده
Recent research has demonstrated that transport of excess fluoride in cystic fibrosis (CF) occurs in the mutated transmembrane conductance channel regulator (CFTR). Since disturbances in these channels are responsible for the symptoms associated with CF, this knowledge that fluoride is also transported through these channels opens ways to achieve a better understanding of how fluoride exacerbates the symptoms of CF or induces CF-like symptoms in individuals without the CFTR genetic anomaly.
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